Custom Synthesis Solutions at Creative Biolabs Enable Optimal Glycoprotein Discovery

January 29 19:15 2021
Creative Biolabs is a professional CRO in the area of therapeutic glycoprotein, which provides first-level customized solutions regarding glycoprotein development. With seasoned scientists and a variety of production platforms, Creative Biolabs can produce the most diverse portfolio of standard or custom therapeutic proteins.

New York, USA – January 29, 2021 – Glycoproteins are formed by covalently connecting certain amino acid residues in oligosaccharide chains and peptide chains with glycosidic bonds, of which the main biological function is the biological recognition of molecules. In recent days, glycoprotein has gradually gained a position in precision medicine due to its close relation to the occurrence and development of many diseases. Regarding this potential diagnostic & therapeutic approach, Creative Biolabs established a center to serve the researchers in this field specifically, offering first-level custom synthesis of glycan, glycopeptide, and glycoprotein.

Chemical and enzymatic methods adopted for synthesis apply to different purposes. A commonly used method for glycopeptide and glycoprotein synthesis is the chemical synthesis that connects two substances via a chemical link, of which there are two strategies that mainly differ at the occasion of the linkage construction. Taking advantage of many natural or artificial enzymatic approaches, the production of related glycoprotein substance is improved on a large scale.

Technicians can handle the synthesis of glycan, a kind of compound made of glycosidically connected monosaccharides, which participates in important processes, including inflammation, metastasis, and bacterial and viral infection. The technical challenge is that there is no template for the synthesis of glycans that are heterogeneous, and several synthetic steps are required in the process. Holding the expertise in synthesis methods, the technicians have developed several strategies to conduct glycan synthesis, involving both chemical and enzymatic methods. The custom glycan synthesis services cover monosaccharide, oligosaccharide, nucleotide sugar, glycolipid, polysaccharide, carbohydrate antigen, etc.

In addition to the synthesis, Creative Biolabs also offers services related to glycoengineering, glycoconjugation, anti-glycoprotein antibody and glyco-based vaccine development, and comprehensive analysis services. A variety of production platforms such as bacteria, mammalian cells, insect cells, yeast cells, and plant cells enable the generation of a wide range of glycoproteins of interest. In addition, several platforms for analytical use help conduct glycoprotein detection, structural analysis, and quantification of glycoprotein.

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Creative Biolabs is a biotechnology service outsourcing company, which is specialized in protein production, engineering, and analysis. Creative Biolabs has organized a team of scientists who are quite knowledgeable and professional in chemistry, biology, and medicine related areas, and it has already been recognized by worldwide clients. After years of exploration and expansion since its establishment, it has accomplished hundreds of projects related to the glycoprotein.

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Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email
Phone: 1-631-830-6441
Country: United States