Bone Resorption Market Expected to Grow Significantly by 2032 Due to Rising Prevalence and Recent FDA Approvals | DelveInsight

May 06 15:31 2025
Bone Resorption Market Expected to Grow Significantly by 2032 Due to Rising Prevalence and Recent FDA Approvals | DelveInsight
Bone Resorption Market Report
The bone resorption market is poised for substantial transformation through 2032, driven by the rising prevalence of osteoporosis and related disorders, an aging population, and significant advancements in targeted therapies. Key bone resorption companies, including Bioventus, Isto Biologics, Kuros Biosciences, OssDsign, BONESUPPORT, Cerapedics, DiscGenics, Osteopore, TherageniX, Stryker, DePuy Synthes, Medtronic, Zimmer Biomet, and Orthofix, among others, are innovating in this landscape.

DelveInsight’s “Bone Resorption – Market Insight, Epidemiology and Market Forecast – 2032” report provides an in-depth understanding of the bone resorption therapeutic market, current treatment practices, and competitive landscape across the United States, EU4 (Germany, Spain, Italy, and France), the UK, and Japan. The report analyzes historical and forecasted bone resorption epidemiological data while delivering crucial insights into emerging therapies, market share of individual treatments, and the evolving competitive landscape in this therapeutic area.

According to the comprehensive analysis, the bone resorption market in the 7MM is projected to experience notable growth during the forecast period (2019-2032), with several pharmaceutical companies actively developing innovative therapeutic approaches to address this significant health challenge.

Download the bone resorption market report to understand which factors are driving the bone resorption therapeutic market @ Bone Resorption Market Trends.

DelveInsight’s Epidemiological studies indicate alarming prevalence rates of conditions associated with pathological bone resorption, particularly osteoporosis. In the US alone, approximately 10 million individuals over age 50 are affected by osteoporosis, with projections indicating a 30% increase by 2030.

Gender differences in bone resorption disorders are noteworthy, with the analysis showing osteoporosis being more prevalent among females compared to males. Furthermore, the prevalence increases significantly with age in both genders. These epidemiological patterns highlight the critical need for gender-specific and age-specific approaches in bone resorption management strategies.

Discover evolving trends in the bone resorption patient pool forecasts @ Bone Resorption Epidemiology Analysis.

The current bone resorption treatment landscape encompasses several approaches, including bisphosphonates, selective estrogen receptor modulators, monoclonal antibodies, and hormone-related therapies. DelveInsight’s analysis reveals that while existing therapies have established efficacy profiles, significant unmet needs remain, particularly regarding long-term safety, patient compliance, and addressing treatment-resistant cases. The market report provides detailed insights into marketed drugs, their mechanisms of action, and their commercial performance across the 7MM.

The bone resorption pipeline shows promising activity, with numerous therapies at various stages of development. DelveInsight’s report highlights emerging drugs in late-stage clinical trials that demonstrate the potential to address current treatment limitations. Key therapies include biosimilars targeting the RANKL pathway, such as RGB-14-P, Bmab 1000, and TVB-009, which are in late-stage trials or nearing approval. Innovative antibody treatments like AGA2118 and SHR-1222, which target sclerostin and DKK1, are also progressing through clinical trials. Research into cathepsin K inhibitors is ongoing, and dual-action agents like romosozumab are already demonstrating real-world benefits. Together, these developments promise more effective and targeted options for managing osteoporosis.

The bone restoration treatment landscape is experiencing some noteworthy developments, particularly with recent FDA approvals and advancements in clinical trials. In March 2025, the FDA approved multiple DENOSUMAB biosimilars, such as BOMYNTRA, OMLYCLO, STOBOCLO, OSENBELT, and CONEXXENCE. Additionally, XBRYK and OSPOMYV received approval in February 2025. These biosimilars have shown equivalent efficacy and safety to the original denosumab in large phase III clinical trials, demonstrating similar improvements in bone mineral density and a reduction in fracture risk.

Discover recent advancements in the bone resorption treatment landscape @ Bone Resorption Recent Developments.

Looking ahead, the bone resorption market is expected to witness significant shifts due to increasing disease awareness, enhanced diagnostic capabilities, and substantial healthcare investments worldwide. Market growth will be further propelled by the aging global population and the rising incidence of associated conditions like osteoporosis. However, challenges remain, including treatment access disparities, reimbursement issues in certain regions, and the need for more personalized therapeutic approaches based on individual patient characteristics and disease manifestations.

DelveInsight’s report provides valuable strategic insights for stakeholders navigating this complex landscape, offering a comprehensive analysis of market trends, barriers, opportunities, and the competitive environment. By understanding the current and future dynamics of the bone resorption market, healthcare providers, pharmaceutical companies, and investors can make informed decisions to address the substantial unmet needs in this therapeutic area and improve outcomes for millions affected by pathological bone resorption worldwide.

Table of Contents

1. Key Insights

2. Executive Summary of Bone Resorption

3. Bone Resorption Competitive Intelligence Analysis

4. Bone Resorption: Market Overview at a Glance

5. Bone Resorption: Disease Background and Overview

6. Bone Resorption Patient Journey

7. Bone Resorption Epidemiology and Patient Population

8. Treatment Algorithm, Current Treatment, and Medical Practices

9. Bone Resorption Unmet Needs

10. Key Endpoints of Bone Resorption Treatment

11. Bone Resorption Marketed Products

12. Bone Resorption Emerging Therapies

13. Bone Resorption: Seven Major Market Analysis

14. Attribute analysis

15. 7MM: Market Outlook

16. Access and Reimbursement Overview of Bone Resorption

17. KOL Views

18. Bone Resorption Market Drivers

19. Bone Resorption Market Barriers

20. Appendix

21. DelveInsight Capabilities

22. Disclaimer

23. About DelveInsight

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Bone Resorption Pipeline Insight

Bone Resorption Pipeline Insight provides comprehensive insights about the bone resorption pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the bone resorption companies, including Bioventus, Isto Biologics, Locate Bio, Kuros Biosciences, OssDsign, BONESUPPORT, Cerapedics, DiscGenics, Osteopore, TherageniX, Stryker, DePuy Synthes, Medtronic, Zimmer Biomet, and Orthofix, among others.

About DelveInsight

DelveInsight is a leading market research and consulting firm specializing in disease-specific insights and therapeutic market analysis. Their reports integrate real-world data, clinical trial findings, and expert interviews to deliver comprehensive industry intelligence.

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